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Concomitant use of oxycodone HCl with CYP3A4 inducers or discontinuation of the CYP3A4 inhibitor could lower oxycodone plasma concentrations, minimize opioid efficacy or, perhaps, result in a withdrawal syndrome inside of a client who had created physical dependence to oxycodone.Advise the two people and caregivers in regards to the risks of respir